林格氏液联合羟乙基淀粉注射液抢救创伤性休克73例

摘要

目的：观察限制性液体林格氏液联合羟乙基淀粉注射液对创伤性休克抢救的临床疗效及安全性。方法选取146例创伤性休克患者，随机分为对照组和观察组，各73例。对照组输注大量等渗盐溶液维持血压>90/60 mmHg，观察组采用限制性液体林格氏液联合羟乙基淀粉注射液治疗，记录并比较两组患者心率、血小板计数（PLT）、凝血酶原时间（PT）、血红蛋白（Hb）等检查结果，多器官功能障碍综合征（MODS）、急性呼吸窘迫综合征（ARDS）、急性肾功能衰竭（ARF）等并发症的发生率和病死率，以及患者复苏后24 h 和48 h 动脉血乳酸水平。结果观察组复苏后心率、平均动脉压、PT 和输液量均显著低于对照组，观察组红细胞压积(HCT)、Hb 和 PLT 均较对照组显著升高（ P 90 / 60 mmHg, the observation group were treated with limited fluid Ringer injection therapy combined with hydroxyethyl starch, recorded and compared two groups of patients heart rate, PLT, PT, Hb etc. as well as the incidence and mortality of patients after resuscitation 24, 48 h arterial blood lactate levels of vital signs, MODS, ARDS, ARF and other complications. Results The study group recovery heart rate, mean arterial pressure, PT, and the infusion were significantly lower than the control group, the observation group HCT, Hb and PLT increased significantly compared with the control group, with a statistically significant difference ( P < 0. 05), the incidence of complications in patients in the observation group and mortality rates were significantly lower than the control group( P < 0. 05), the number of patients in the observation group arterial blood lactate levels return to normal standards signif-icantly higher, with a statistically significant difference( P < 0. 05 ). Conclusion Ringer limiting joint hydroxyethyl starch liquid injection rescue patients with traumatic shock effect is remarkable, safe, reliable, effective guarantee of organ perfusion and improve prognosis, wor-thy of clinical application.