天麦消渴片联合吡格列酮治疗初发2型糖尿病46例

摘要

Objective To investigate the effect of Tianmai Xiaoke Tablets combined with pioglitazone in treating newly diagnosed type 2 diabetes mellitus(T2DM) and its influence on insulin resistance indez(HOMA-IR) and the β cell function indez(HOMA-β). Methods Totally 92 patients with newly diagnosed T2DM were admitted to our hospital from March 2013 to March 2014 and random-ly divided into the observation group and the control group,46 cases in each group. The two groups all were given the pioglitazone treatment;the observation group was added with Tianmai Xiaoke Tablets. Results FPG,FINS,HOMA-IR and HOMA-β after treatment in the two groups were superior to those before treatment( P < 0. 05),moreover the various indezes in the observation group were sig-nifianly better than those in the control group( P < 0. 05). Conclusion Tianmai Xiaoke Tablets combined with pioglitazone can effec-tively inhibit insulin resistance,protect the β cell function,has good clinical efficacy,and is worthy of clinical promotion.%目的：观察天麦消渴片联合吡格列酮治疗初发2型糖尿病的疗效并探讨对患者胰岛素抵抗指数（HOMA－IR）及β细胞功能指数（HOMA－β）的影响。方法选择医院2013年3月至2014年3月收治的患者92例，随机分为观察组与对照组，各46例。两组患者均给予吡格列酮治疗，观察组患者加用天麦消渴片治疗。结果两组患者治疗后的空腹血糖（FPG）、空腹胰岛素（FINS）、HOMA－IR， HOMA－β均明显优于治疗前（ P＜0.05），且观察组患者各指标改善明显优于对照组（ P＜0.05）。结论天麦消渴片联合吡格列酮可有效抑制胰岛素抵抗，且能够保护β细胞功能，具有良好的临床疗效，值得推广。