目的：探讨子宫内膜异位症合并不孕患者腹腔镜术后促性腺激素释放激素激动剂（GnRH－α）治疗的妊娠结局及临床疗效。方法将医院2012年10月至2015年6月收治的子宫内膜异位症合并不孕患者80例随机均分为观察组和对照组，各40例，对照组单纯采用腹腔镜术治疗，观察组在此基础上加用GnRH－α治疗，比较两组患者术后1年妊娠、复发情况及妊娠结局（自然流产、异位妊娠、早产、足月产、自然分娩、剖宫产）。结果观察组患者术后1年妊娠率为60.00％，显著高于对照组的32.50％；术后1年复发率为2.50％，显著低于对照组的17.50％（ P＜0.05）。观察组患者术后自然分娩率和剖宫产率与对照组比较，差异有统计学意义（ P＜0.05）。两组足月产率、早产率、异位妊娠率及自然流产率比较，差异均无统计学意义（ P＞0.05）。结论采用GnRH－α治疗子宫内膜异位症合并不孕患者腹腔镜术后有助于提高妊娠率，减少复发，对妊娠结局具有一定影响，临床可推广应用。%Objective To investigate the pregnanct outcome and efficact in patients with endometriosis associated infertilitt bt the treat-ment of GnRH-αafter laparoscopic surgert. Methods 80 patients with endometriosis associated with infertilitt in the hospital from Oc-tober 2013 to June 2016 were randomlt divided into the observation group ( 40 cases ) and the control group ( 40 cases ) . The control group was treated with laparoscopic operation, and the observation group was treated with gonadotropin releasing hormone agonist ( GnRH-a ) on the basis of the above treatment. The pregnanct and recurrence after 1 tear, the pregnanct outcome ( spontaneous abor-tion, ectopic pregnanct, premature delivert, term birth, natural childbirth, cesarean section ) of two groups were compared. Results After one tear, the rate of pregnanct rate in observation group ( 60. 00%) was significantlt higher than the control group ( 32. 50%);postop-erative recurrence rate of 1 tear ( 2. 50% ) was significantlt lower than the control group ( 17. 50% ) ( P 0. 05 ) . Conclusion The treatment of GnRH-αafter laparoscopic surgert in patients with endometriosis associated infertilitt is helpful to improve the pregnanct rate and can reduce the recurrence. It has a certain impact on the outcome of pregnanct, which is wortht of clinical promotion.
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