Objective To investigate the clinical characteristics hospitalized patients due to drug- induced hypoglycemia and provide references for clinical practice. Methods The data of patients admitted to our endocrinology department due to drug-induced hypo-glycemia were collected from January 2010 to December 2014. Results A total of 27 patients with drug-induced hypoglycemia in hospital, including 21 cases of diabetes patients, 6 patients with non-diabetic, 16 cases of men and women in 11 cases, age 44-84, the average age ( 66 ± 13. 2 ) . As for the clinical manifestations of the hypoglycemia, 9 cases had hypoglycemia symptoms such as dizziness, palpitation, sweating, fatigue;18 patients with disturbance of consciousness characterized by unconsciousness, nonsense, grow weary of con-sciousness, coma. The blood suga checked when hypoglycemia onset was ≤3. 9 mmol/L, The lowest was 0. 9 mmol/L, the suspect drugs with the highest frequency is a sulfonylureas and insulin. Conclusion The hospitalization due to drug-induced hypoglycemia has more rapid onset with great harm, and the victim are mostly elderly patients. We should strengthen drug education, and prevent drug-induced hypoglycemia.%目的：探讨药源性低血糖住院患者的临床特点，为临床用药提供参考。方法收集医院内分泌科2010年至2014年收治的因药源性低血糖入院27例患者的临床资料并进行分析。结果共27例患者因药源性低血糖入院，其中糖尿病21例，非糖尿病6例；男16例，女11例；年龄44~84岁，平均（66±13.2）岁；9例表现为低血糖症状如头晕、心悸、大汗、乏力，18例患者伴发意识障碍，表现为意识不清，胡言乱语，意识丧志，昏迷；低血糖发作时查血糖均不超过3.9 mmol/L，其中最低1例仅0.9 mmol/L。怀疑药物频次最高的是胰岛素和磺脲类药物。结论因药源性低血糖入院多起病急，危害大，且高龄患者居多。应加强用药教育，预防药源性低血糖的发生。
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