环磷酰胺等6种药物联合治疗34例晚期乳腺癌

摘要

Purpose：To observe the curative effects and side effects obtained from combined chemotherapy of advanced breast cancer with “CMFBDP”.Methods：Thirty four cases with stage Ⅲ and Ⅳ breast cancer were treated with the combined chemotherapy of “CMFBDP”.Results：The response rate in primary treatment patients was 80%. The response rate in recurrent patients was 65.5%. The major side effect was nausea and vomiting. Conclusions：The combined chemotherapy of CMFBDP is an effective and safe treatment in advanced breast cancer%目的：观察环磷酰胺、甲氨蝶呤、氟尿嘧啶、平阳霉素、顺氯氨铂、强的松联合(CMFBDP方案)治疗晚期乳腺癌的疗效和毒副反应。方法：34例临床Ⅲ、Ⅳ期乳腺癌患者行CMFBDP联合方案为主的治疗。结果：初治组有效率80%，复治组有效率65.5%。毒副反应主要为恶心呕吐。结论：CMFBDP联合化疗方案治疗晚期乳腺癌是有效和安全的。