药物性血尿52例临床分析

摘要

Objective:To explore the cause of drug-induced hematuria. Methods:To analyse for clinical information of 52 cases of drug-induced hematuria in the data and reason. Results:The drugs causing hematuria were sulfa drugs, diclofenac, indocin, centamyein, cefradine, cefletin, ciprofloxacin, oflxaein and amethopterin.These patients had historical to use related drugs. Clinical maniteslations: hematufia, cryslats by microscopic examination of uria, skin rash in a small mumber of patients. Old people were more (51.92%) in these patients. All patients were fully recovered by stoping drugs and symptomatic treatment. All patients recovered not recured by following and visiting them at six months. Conclusion:In rnorder to avoid occurrence of the disease, clinical doctors should master strictly medication indications and prevent to abuse drugs and try to use fewer or no drugs of nephrotoxicity particularly in elderly patients and educate patients to use drugs under the guidance of doctor as much as possible and no blind.%目的:探讨药物所致血尿的病因.方法:对52例药物性血尿的临床资料进行数理分析.结果:表明引起血尿的药物有磺胺类、双氯酚酸、消炎痛、庆大霉素、头孢拉啶、头孢氨苄、环丙沙星、氧氟沙星、甲氨蝶呤.患者有使用相关药物史,临床表现为血尿,镜检尿液有结晶体,少数患者有皮疹,老年患者较多(51.9%).停用药物及对症处理后痊愈.随访6个月无复发.结论:为避免该症的发生,临床医生应严格掌握用药指征,防止滥用药物,尽量少用或不用肾毒性药物,特别是老年患者,并教育患者应尽可能在医生指导下用药、不要盲目用药.