早期机械通气治疗急性左心衰竭肺水肿的效果观察

摘要

Objective To explore the effect of early mechanical ventilation in the treatment of acute left heart failure and pulmonary edema. Methods 200 patients with acute left heart failure and pulmonary edema from January 2010 to January 2014 in our hospital were selected and randomly divided into the observation group and the control group,100 cases in each group.The control group was treated with routine therapy,the observation group was treated with early me-chanical ventilation therapy on the basis of the control group.The total effective rate,respiratory rate,arterial blood gas index,left ventricular ejection fraction (LVEF),stroke volume (SV),cardiac output (CO),cardiac index (CI) in two groups before and after treatment was compared. Results The total effective rate of the observation group was higher than that of the control group,with significant difference (P<0.05).The level of RR,PaCO2 in two groups after treatment was lower than that before treatment,with significant difference (P<0.05).The level of SaO2、PaO2 in two groups after treatment was higher than that before treatment,with significant difference(P<0.05).The level of RR,PaCO2 in the observation group af-ter treatment was lower than that in the control group after treatment,with significant difference (P<0.05).The level of SaO2、PaO2 in the observation group after treatment was higher than that in the control group after treatment,with signif-icant difference (P<0.05).The level of LVEF、SV、CO、CI in the observation group was higher than that in the control group,with significant difference(P<0.05). Conclusion The short term effect of early mechanical ventilation on the basis of conventional therapy in the treatment of acute left heart failure and pulmonary edema is remarkable,it is worthy of clinical promotion and application.%目的：探讨早期机械通气治疗急性左心衰竭肺水肿的效果。方法选取本院2010年1月~2014年1月收治的急性200例左心衰竭肺水肿患者作为研究对象，随机分为研究组和对照组，各100例。对照组给予常规治疗，观察组在对照组的基础上给予早期机械通气治疗。比较两组治疗前后的总有效率、呼吸频率、动脉血气指标、左心室射血分数（LVEF）、每搏输出量（SV）、心排血量（CO）、心脏指数（CI）。结果观察组的总有效率显著高于对照组，差异有统计学意义（P<0.05）。两组治疗后的RR、PaCO2水平显著低于治疗前，差异有统计学意义（P<0.05）。两组治疗后的SaO2、PaO2水平显著高于治疗前，差异有统计学意义（P<0.05）。观察组治疗后的RR、PaCO2水平显著低于对照组治疗后，差异有统计学意义（P<0.05）。观察组治疗后的SaO2、PaO2水平显著高于对照组治疗后，差异有统计学意义（P<0.05）。观察组的LVEF、SV、CO、CI水平显著高于对照组，差异有统计学意义（P<0.05）。结论在常规治疗的基础上采用早期机械通气治疗急性左心衰竭肺水肿短期效果显著，值得临床推广应用。