亚急性甲状腺炎患者超敏C反应蛋白的变化及临床意义

摘要

Objective To detect the changes of serum high sensitivity C- reactive protein(hs-CRP) in patients with subacute thyroiditis(SAT) and to explore its clinical application. Methods Hs-CRP levels were detected in 60 subacute thyroiditis patients and 60 healthy individuals simultaneously by using the emulsion enhancement transimission turbidimetric method. Results The hs-CRP level had increased significantly among subacute thyroiditis patients(P < 0.01). The hs-CRP level had decreased significantly after glucocorticosteroid treatment in subacute thyroiditis patients(P < 0.01). Conclusion Hs-CRP is fast response protein and may be useful marker of systemic inflammation. Hs-CRP can be used as an indicator of early diagnosis in the patients of subacute thyroiditis.%目的探讨超敏C反应蛋白（hs-CRP）在亚急性甲状腺炎患者中的变化及临床意义。方法对60亚急性甲状腺炎患者和60例健康体检者检测hs-CRP，采用乳胶增强透射比浊法测定hs-CRP。结果 hs-CRP水平在亚急性甲状腺炎患者中均显著性升高（P＜0.01）。亚急性甲状腺炎患者经过糖皮质激素治疗后，hs-CRP有显著下降（P＜0.01）。结论 hs-CRP可反映出机体炎症活性，通过检测hs-CRP有助于早期判断亚急性甲状腺炎，并了解亚急性甲状腺炎病情。