生殖道感染对未足月胎膜早破母婴围产结局的影响

摘要

Objective To investigate the influence of genital tract infection on the maternal-infant outcome in preterm premature rupture of the membranes(PPROM). Methods 150 cases were divided into 2 groups according to the existence of genital tract infection,infected group(95 cases)and non-infected group(55 cases) respectively. The maternal-infant outcomes were analyzed and compared between two groups. Results The abnormal rate of genital tract infection was 63.3%(95/150). Compared with non-infected group, the expectation therapy time was shortened than that in infected group [(5.27±2.53)d/(11.89±3.26)d,(P < 0.05)]. The incidence rates of caesarean section, chorioamnionitis, fetal distress, neonate asphyxia, neonate death were increased significantly in infected group than those in non-infected group(P < 0.05). The incidence rates of neonatal infections and puerperal infections had no significance differences between two groups(P > 0.05). Conclusion Genital tract infection is the leading factor in PPROM. The treatment of genital tract infection can reduce the occurrence of PPROM and improve the maternal-infant outcomes.%目的：探讨生殖道感染对未足月胎膜早破（PPROM）母婴围产结局的影响。方法对150例未足月胎膜早破患者临床资料进行回顾性分析，按照生殖道感染情况分为感染组（95例）和未感染组（55例），比较两组患者母婴围产期并发症发生率。结果未足月胎膜早破生殖道感染发生率63.3%（95/150）。感染组平均期待治疗时间（5.27±2.53）d短于未感染组（11.89±3.26）d，差异有统计学意义（P＜0.05）。感染组剖宫产率、绒毛膜羊膜炎发生率大于未感染组，差异具有统计学意义（P＜0.05）。感染组胎儿窘迫、新生儿窒息、新生儿死亡率均大于未感染组，差异具有统计学意义（P＜0.05）。两组产褥感染和新生儿感染率比较，差异无统计学意义（P＞0.05）。结论生殖道感染是导致未足月胎膜早破的主要因素，对生殖道感染的治疗可降低未足月胎膜早破的发生率，改善母婴围产结局。