急诊不同治疗时机对急性肺栓塞疗效及预后影响分析

摘要

Objective To investigate clinical efficacy and prognosis of different timing of treatment of acute pulmonary embolism. Methods 68 patients with acute pulmonary embolism in our hospital from January 2011 to June 2013 were divided into the control group (34) and the study group(34) according diagnosis treatment time whether or not more than 2 weeks. Both groups were given the same thrombolytic anticoagulant therapy and the corresponding care. Results After thrombolysis combined anticoagulant therapy, the respiratory rate and heart rate of two groups were significantly decreased; PaO2 and PaCO2 levels were significantly improved(P < 0.01). The total effective rate of study group(94.12%) was higher than that of the control group (76.47%)(P<0.05); The incidence of the primary endpoint of the study group (14.71%) was significantly lower than the control group (35.29%)(P<0.05). Conclusion Patients with acute pulmonary embolism has diverse clinical manifestations, is prone to misdiagnosis;The diagnosis and treatment in two weeks will help improve clinical efficacy, significantly improv the prognosis of patients.%目的：探讨急诊不同治疗时机对急性肺栓塞患者的疗效及预后的影响。方法选择2011年1月~2013年6月期间我院收治的68例急性肺栓塞患者，按确诊治疗时间是否超过2周分为两组，超过2周的为对照组（34例），不足2周的为研究组（34例），两组患者均给予相同的溶栓联合抗凝治疗及相应的护理工作。结果经过溶栓联合抗凝治疗之后，两组患者的呼吸频率与心率明显减弱，PaO2、PaCO2水平均明显改善，相比治疗前差异有统计学意义（P＜0.05）；治疗后研究组的心率与动脉血氧分压PaO2相比对照组有明显改善，差异有统计学意义（P＜0.01）；研究组患者的总有效率为94.12%，对照组患者的总有效率为76.47%，两组患者相比差异有统计学意义（P＜0.05）；研究组的主要终点事件发生率（14.71%）显著低于对照组（35.29%），差异有统计学意义（P＜0.05）。结论急性肺栓塞的临床表现多样，容易发生误诊，在2周内确诊并治疗有利于提高临床疗效，明显改善患者的预后。