目的：探讨我院门诊西药房调血脂药联合用药使用情况。方法对我院2011年5月～2013年12月所有门诊西药房的使用处方进行收集，对资料进行回顾性分析。结果经过统计后，在我院门诊西药房开出的调血脂处方有1294张。其中数量最多的为阿托伐他汀片（20mg），数量为718张，其次为辛伐他汀片（20mg），数量为216张。所有联合使用调血脂药物的处方60张，占总处方的4.6％。调血脂药物联合应用如下：（1）普罗布考与他汀类药物联合使用的处方有50张，占83.4％；（2）弹性酶肠溶片与他汀类联合使用的处方有5张，占8.3％；（3）调血脂药物联合使用不合理的处方5张，占8.3％。结论与混合型高脂血症患者相比，单独使用一种降脂药物进行治疗后，难以对血脂异常疾病进行有效的治疗，但是为了患者的安全考虑，不同药物的联治疗在临床上较为少见，通过何种联合用药的方式帮助患者彻底的治疗血脂异常，还需要进一步的研究。%Objective To study the usage of drug combination on lipid-regulating drugs in outpatient dispensary for western medicine. Methods All outpatient pharmacy prescriptions which were in the hospital from May 2011 to December 2013, were collected and analyzed retrospectively. Results After statistics, there are 1294 pieces of lipid regulating prescription prescribed in outpatient pharmacy of our hospital, of which the largest number were atorvastatin tablets (20mg) in 718 pieces, followed by Simvastatin Tablets (20mg) in 216 pieces. The prescriptions combined use of lipid regulating drug were 60 pieces, 4.64% of total prescriptions. The following application of lipid regulating drug: (1) There were 50 pieces prescriptions of probucol combined with the statins,accounted for 83.4%; (2)There were 5 prescriptions prescriptions of elastase entric-coated tablets combined with statins, accounted for8.3%; (3)There were 5 prescriptions of unreasonable combined use on lipid-regulating drugs, accounted for8.3%. Conclusion Compared with the mixed drug treatment of hyperlipidemia patients, using a lipid-lowering drugs is difficult to carry out treatment effective for abnormal blood lipid, but in consideration of the safety, the combined use of different drugs is rare in clinic. It needs further research, how to combination therapy can treat patients with dyslipidemia.
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