Objective To explore the curative effect of concurrent radiochemotherapy in the treatment of locally advanced non-small cell lung cancer and its influence on the life qualities of patients. Methods The patients with locally advanced non-small cell lung cancer (NSCLS) who were in our hospital from January 2011 to February 2014 were divided into group A (55 cases) and group B(54 cases), group A received concurrent radiochemotherapy and group B received sequential radiochemotherapy. The curative effect and adverse reactions of the two groups were summarized, the life qualities before and after treatment were compared,and the data were analyzed by chi-square test. Results In group A, the curative effect rate,2-year survival rate, and total incidence of bone marrow suppression were all obviously higher than those of group B (P<0.05), the life qualities after treatment were obviously improved than those before (P<0.05), and the constituent ratio of patients with good life qualities rose to 58.18%from 32.73%before treatment. Conclusion Concurrent radiochemotherapy is effective in the treatment of locally advanced NSCLS, which adverse reactions can be tolerated while improving the life qualities of patients. It is worthy of recommendation.%目的：探讨同步放化疗治疗局部晚期非小细胞肺癌的疗效及对患者生活质量的影响。方法将2011年1月～2014年2月收治的局部晚期非小细胞肺癌（NSCLC）患者分为同步放化疗组（A组，55例）与序贯放化疗组（B组，54例），A组采用同步放化疗方案治疗，而B组采用序贯放化疗方案治疗。统计两组的疗效和不良反应，评估治疗前后的生活质量，利用Pearsonχ2检验和行×列表χ2检验等分析数据。结果A组的有效率、2年生存率和骨髓抑制的总发病率均明显高于B组（P＜0.05）。与治疗前相比，A组患者的生活质量在治疗后出现明显变化（P＜0.05），其中患者生活质量良好的构成比由治疗前的32.73%增加到58.18%。结论同步放化疗方案在局部晚期NSCLC中的疗效非常显著，不良反应可耐受，同时可提升患者的生活质量，值得推荐。
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