Objective: To observe the antipyretic and anti -inflammatory effects of Qingyan Oral Liquid. Methods: Qingyan Oral Liquid was used as the research object. The antipyretic activity of Qingyan Oral Liquid was observed in fever rats caused by 2,4-dinitrophenol, and the inflammatory activity was observed in ear edema mice caused by xylen and paw swelling rats caused by carrageenin. Results: Compared with the blank control group (physiological saline group), Qingyan 0 -ral Liquid showed significant antipyretic activity in rats with high temperature induced by 2,4-dinitrophenol (P<0.05), and significant anti-inflammatory activity in rats with paw swelling induced by carrageenin and mice with ear edema induced by xylene (all P<0.05). Conclusion: Qingyan Oral Liquid has notable effects of antipyretic and anti-inflammatory.%目的:观察清咽口服液的解热抗炎作用.方法:以清咽口服液为研究对象,采用2,4-二硝基苯酚致大鼠发热法研究其解热作用,采用二甲苯致小鼠耳肿胀法和角叉菜胶致大鼠足肿胀法研究其抗炎作用.结果:与空白对照组(生理盐水组)比较,清咽口服液能显著降低2,4-二硝基苯酚致大鼠发热模型的体温(P<0.05),对二甲苯致小鼠耳肿胀及角叉菜胶致大鼠足肿胀均有显著的抑制作用(均P<0.05).结论:清咽口服液具有明显的解热、抗炎作用.
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