Objective: To investigate the diagnosis value of cardiac troponin (cTnT) and creatine kinase MB isoenzyme (CK-MB) in unstable angina heart failure, in order to provide reference for clinical treatment. Methods: Unstable angina heart failure patients were selected as observation group (30 cases) in our hospital from April 2009 to April 2011, and healthy people without cardiovascular disease were selected as control group (30 cases). cTnT and CK-MB leved were de -tected in two groups. Results: In observation group the blood levels of cTnT in the incidence of early, middle and late were higher than that of control group, the differences were statistically significant (P<0.05). The levels of blood CK-MB in the incidence of early and middle of observation group were higher than that of control group, the differences were statisti -cally significant (P<0.05). In the incidence of late, the levels of blood CK-MB in observation group was slightly higher than that of control group, but there was no significant difference (P>0.05). Conclusion: CK-MB and cTnT as the recent development of high-energy indices of myocardial injury, can conduct as the specific marker for unstable heart failure early diag -nosis, and cTnT level in the diagnosis is more sensitive than CK-MB.%目的:探讨肌酸激酶MB同工酶(CK-MB)、心肌肌钙蛋白(cTnT)对于不稳定型心力衰竭的诊断价值,为临床治疗提供参考.方法:2009年4月~2011年4月随机收集我院临床诊断为不稳定型心力衰竭患者作为观察组(30例),收集同期无心血管疾病的健康者作为对照组(30例),对两组的cTnT和CK-MB水平进行比较.结果:观察组与在发病早期、中期、晚期3个时间点的血cTnT水平均明显高于对照组,差异有统计学意义(P<0.05).观察组的血CK-MB水平在发病早期和中期均高于对照组,差异有统计学意义(P<0.05),在发病晚期,观察组血CK-MB水平较对照组稍高,但差异无统计学意义(P>0.05).结论:CK-MB与cTnT作为近年来发展起来的检测心肌损伤的高能指标,可以作为不稳定型心力衰竭早期诊断的特异性指标,血cTnT水平的变化比CK-MB更敏感.
展开▼
