笑气在人工流产手术中的临床疗效观察

摘要

Objective: To investigate whether the use of misoprostol and lidocaine combined with nitrons oxide has significant sedative effects or not during the operation and to investigate the specific effects on patients, and therefore to reveal the feasibility of applying misoprostol and lidocaine combined with nitrous oxide to sedate during the abortion operation.Methods: 968 pregnant women in our hospital from June 2006 to June 2010, who voluntarily demand to terminate pregnancy with the pregnancy period of 4-8 weeks and gestational sacs of 5-40 mm and who were free of contraindication.According to the principle of knowing and agreeing, they were divided into two groups, one using misoprostol and lidocaine and the other adding nitrous oxide with each group of 484 patients and the induced abortion operations were carried out with the clinical efficacy being observed.Results: In the group of using misoprostol and lidocaine, the number of cases with obvious sedative effect was 363 cases (75.0％), effective 97 cases (20.04％) and insufficient 24 cases (4.96％); in the group of using misoprostol and lidocaine combined with nitrous oxide, the number of cases with obvious sedative effect was 421 cases (86.98％), effective 53 cases (10.95％) and insufficient 10 cases (2.07％).The difference between the two groups was statistically significant (P＜0.05).Conclusion: The sedative effect of using misoprostol and lidocaine combined with nitrous oxide in induced abortion operation is significant.%目的:探讨米索前列醇、利多卡因联合笑气吸入在手术期间是否起到明显的镇痛作用以及对受术者的具体影响,以揭示在人工流产手术中应用米索前列醇、利多卡因联合笑气进行镇痛的可行性.方法:选择我院2006年6月～2010年6月因各种原因自愿要求终止妊娠,妊娠时间为4～8周,孕囊为5～40 mm,无用药禁忌证的妊娠妇女968例,根据知情同意原则分为单纯使用米索前列醇、利多卡因组及加用笑气吸入组,各484例,进行人工流产手术,观察临床效果.结果:米索、利多组术中镇痛效果好363例(75.0%),有效97例(20.04%),差24例(4.96%);米索、利多联合笑气组镇痛效果好421例(86.98%),有效53例(10.95%),差10例(2.07%),两组比较,差异有统计学意义(P<0.05).结论:米索前列醇、利多卡因联合笑气在人工流产手术中的镇痛效果显著.