糖尿病合并心肌梗死的分析

摘要

目的 分析糖尿病(diabetes mellitus,DM)合并心肌梗死患者(acute myocardial infarction,AMI)的冠脉病变及临床特点.方法 回顾性分析217例心肌梗死患者的临床资料,根据是否合并糖尿病,分为糖尿病组(DM组)和非糖尿病组(NDM组),对比分析其冠脉病变特点、临床症状和梗死部位.结果 DM组血糖(BG)、总胆固醇(TC)、三酰甘油(TG)水平均高于NDM组(P＜0.05或P＜0.01)；DM组患者冠状动脉双支、三支病变和中度、重度狭窄程度发生率明湿高于NDM组(P＜0.05或P＜0.01)；DM组患者高血压、非典型胸痛、心律失常、心力衰竭、心源性休克和肺部感染发生率均明显高于NDM组(P＜0.05或P＜0.01)；DM组心肌多部位梗死和无Q波型发生率与NDM组比较差异有统计学意义(P ＜0.05或P＜0.01).结论 糖尿病合并心肌梗死患者冠脉病变和临床症状比非糖尿病心肌梗死患者严重.%Objective To analyze the characteristics of coronary lesions and clinical symptoms of patients with diabetes mellitus (DM) combined with acute myocardial infarction (AMI). Methods Clinical data of 217 cases of myocardial infarction patients were analyzed retrospectively, and all patients were divided into the diabetic mellitus group (DM group) and non-diabetic mellitus group (NDM group) according to whether combined with mellitus diabetes or not. The coronary lesion characteristics, clinical symptoms and infarction area of the two groups were comparative analyzed. Results Blood glucose (BG), total cholesterol (TC), triglyceride (TG) levels of DM group were all higher than those of the NDM group (P < 0.05 or P < 0.01); compared with the NDM group patients, incidence of double-vessels, three-vessels lesion, moderate and severe degree of coronary artery stenosis in the DM group were significantly higher (P < 0.05 or P < 0.01); hypertension, atypical chest pain, arrhythmia, heart failure, cardiogenic shock and pulmonary infection of patients in the DM group were significantly higher than the NDM group (P < 0.05 or P < 0.01); compared with the NDM group, incidence of myocardial multi-site infarction and non-Q wave in the DM group had significantly statistical differences (P < 0.05 or P < 0.01). Conclusion Coronary lesions and clinical symptoms of mellitus diabetic patients combined with myocardial infarction are more serious than non-diabetic patients with myocardial infarction.