2微米激光与等离子电切治疗非肌层浸润性膀胱肿瘤疗效比较的Meta分析

摘要

Objective To compare the efficacy of 2 micron laser resection and plasmakinetic resection for superficial bladder tumor.Methods Retrieved published comparative studies 2 micron laser resection and plasmakinetic resection for superficial bladder tumor,and pooled the data from eligible studies (Meta-analysis).Odds ratio (OR) and its 95％ confidence interval (CI) were used as the measurement parameter of efficacy comparison.The statistical analyses were performed using Revman 4.2 software.Results Five trials including 177 cases were treated with 2 micron laser resection and 168 cases with plasmakinetic resection.Pooling data showed the operative time and postoperative recurrence were not significantly different between the 2 groups (P＞ 0.05),however,compared with elect plasmakinetic resection group,fewer complications in 2 micron laser group,the difference was statistically significant (P ＜ 0.01).Conclusion 2 micron laser resection of superficial bladder tumor is safe,compared to plasmakinetic resection of bladder tumors,this surgery has some advantages on avoiding complications.%目的 比较2微米激光与等离子电切治疗非肌层浸润性膀胱肿瘤的疗效.方法 收集已发表的关于2微米激光和等离子电切治疗非肌层浸润性膀胱肿瘤的国内外文献,针对结果进行统计学综合(Meta)分析.采用优势比(OR)及95％置信区间(95％ CI)作为评价比较疗效,统计学分析采用Revman 4.2软件.结果 共5篇文献符合标准纳入,177例2微米激光组和168例等离子电切组进行分析.Meta分析显示:两组比较肿瘤的复发和手术时间的差异均无统计学意义(P＞ 0.05),2微米激光组并发症少于等离子电切组,差异有高度统计学意义(P＜0.01).结论 2微米激光治疗非肌层浸润性膀胱肿瘤安全可靠,与等离子电切比较,在避免并发症方面有一定优势.