骨骼肌萎缩防治研究进展

摘要

骨骼肌萎缩是指骨骼肌质量的减少及肌肉功能的降低,常见原因包括长期营养不良、局部肢体或者全身性的运动减少或者缺失、失神经支配等.查明病因并去除致病原因是预防和治疗疾病的重要前提,而对于废用性骨骼肌萎缩、增龄性骨骼肌萎缩这些在致肌萎缩因素无法避免或在一段时期内无法去除的情况下,如何防治骨骼肌萎缩尤显意义深远.本文从中药、西药、生物制品以及电磁刺激、热应激治疗、针灸和基因治疗等方面综述了肌肉萎缩防治的研究成果,也强调了运动锻炼防治肌萎缩的重要作用.%Skeletal muscle atrophy refers to the mass loss and the functional incapacitation of the muscle,which usu ally caused by the long time of malnutrition,single limb uselessness,or denervation.It is essential to find out the causes or the etiology and to cancel them for the effective treatment and prevention of the diseases.As to the skeletal muscle atrophy caused by the weightlessness,uselessness or aging,the conditions are unavoidable or can't be removed for a special duration,which was deserved to study in the long run.The article summarized the research findings on the skeletal muscle atrophy prevention and treatment in different fields such as Chinese traditional medicines,western medicines,biological products,acupuncture,gene treatment and so on.Further more,different exercises were emphasized which were crucial to prevent and even to treat the skeletal muscle atrophy.