上海市高行老年社区射血分数保留的心力衰竭危险因素分析

摘要

目的 了解社区老年人射血分数保留的心力衰竭(HFpEF)的患病率情况,探讨导致老年人HFpEF发生的危险因素.方法 在2013年6～10月对高行老年社区居民进行整群抽查并分为HFpEF组与对照组;通过Logistic回归模型来探讨导致HFpEF发生的独立危险因素.结果 本次研究共发放调查问卷4000份,回收有效问卷3950份,有效率为98.75％.其中HFpEF患者1312例,对照组人群2638名.两组体重指数正常、超重、肥胖的分布差异有统计学意义(P＜0.05).Logistic回归模型提示,当调节变量为年龄、性别、收缩压、肥胖、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)与超敏C反应蛋白时,高龄、女性和低HDL-C是HFpEF发生的独立危险因素(P＜0.05).结论 射血分数保留的心力衰竭在高行社区老年人群中的患病率较高;其中,高龄、女性、较低的HDL-C是发生射血分数保留的心力衰竭的高危因素.%Objectives To estimate the prevalence of heart failure with preserved ejection fraction (HFpEF) in elderly community,and to discuss the risk factors.Methods All target individuals were included in Gaohang communities from June to October in 2013.And they were divided into HFpEF group and control group.Step-wise Logistic regression was used to explore risk factors of HFpEF.Results A total of 4000 questionnaires were distributed to the community elderly.There were 3950 valid questionnaires and the effectives rate of 98.75％.There were 1312 patients with HFpEF and 2638 control individuals.There were significant difference between two groups in composition ratio of normal weight,overweight and obesity (P ＜ 0.05).The regression model indicated that elderly age,female gender and lower HDL-C level were risk factors of HFpEF (P ＜ 0.05),when adjusted variables included gender,age,SBP,obese,HDL-C,LDL-C and hs-CRP.Conclusion The prevalence of HFpEF is higher in elderly community population in Shanghai.Elderly age,female gender and lower HDL-C level are risk factors of HFpEF.