目的:探讨三维(3D)打印技术颅底肿瘤精准手术治疗中的应用.方法:对1例感觉头痛不适,双侧视力渐进性下降至左眼失明的45岁男性患者,进行磁共振(MR)平扫检查发现颅底有占位性病变,遂行头颅CT血管成像(CTA)、3.0T MR检查获得CT和MR的医学数字成像及通信(DICOM)数据,输入计算机进行立体模拟建模,而后打印出三维重建模型.结果:三维重建模型清晰地显示出颅底肿瘤的解剖结构,反映肿瘤所在的三维空间及周围血供,在其指导下完成肿瘤精准、完整地切除,并尽可能保全周围正常脑组织,且减少了整台手术时间.结论:3D打印技术应用于颅底肿瘤的治疗,能清晰显示解剖结构,辨识肿瘤毗邻血管,在避免遗漏肿瘤的同时,更有效地辅助术前规划,对颅底的复杂手术提升了安全性、加快了手术速度,提高手术的精确性,在神经外科精准手术治疗方面具有极大的应用前景.%Objective:To investigate the significance of 3D printing technology in the treatment of skull base tumor.Methods: A 45-year-old male patient who felt headache and discomfort had progressive loss of vision to blindness in the left eye. Using MR plain scan found that there was a skull base tumor, so the patient was examined by brain CTA and 3.0T MR to obtain medical digital imaging of CT and MR and DICOM data which were input into computer for establishing three-dimensional model, and then printed it.Results: 3D reconstruction model can clearly display the anatomical structure of skull base tumor, three-dimensional space and peripheral blood around skull base tumor. Under the guidance of this new technology, the tumor was completely removed and the surrounding normal brain tissue was preserved as much as possible. The whole operation time was greatly reduced at the same time.Conclusion: The treatment of 3D printing technology is applied in skull base tumors can clearly display the anatomical structure, distinguish adjacent vessels around tumor; when it avoids missing tumor, also can more effectively assist preoperative planning, enhance the security for complex skull base surgery, accelerate the operation speed, improve operation accuracy; it has great application prospect in the precise treatment of neurosurgery.
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