基于个性化脉搏波传导参数的连续血压测量方法研究

摘要

Objective To establish a continuous blood pressure measurement model based on personalized pulse wave transmission parameters. Methods ECG parameters and ifnger pulse waves of 18 subjects were continuously measured and recorded in exercise tests and their blood pressures (BP) were also recorded every 2 minutes with dynamic BP monitor. The exercise tests of all the 18 subjects were conducted repeatedly one week later. A linear model between pulse wave translation time (PWTT) and systolic blood pressure (SBP) was constituted through linear minimum mean square error estimation. Results There is a good linear relationship between PWTT and SBP of the same subject (r2=0.91±0.06) and the test error of the linear model with nice stability is (3.48±1.69) mmHg. However, it is very dififcult to build a uniifed linear model for all subjects (r2=0.14). Conclusion It is feasible to measure blood pressure continuously based on personalized pulse wave transmission parameters, which can contribute to the realization of sleeveless continuous blood pressure measurement.%目的：建立基于个性化脉搏波传导参数的连续血压测量方法模型。方法对18名受试者进行了运动实验，在运动实验过程中连续记录受试者的心电和手指容积脉搏波，同时利用动态血压计每2 min采集受试者的血压；每个受试者间隔1周的时间进行第二次实验；采用最小均方误差线性估计的方法来建立脉搏波传导时间和收缩压之间的线性模型。结果同一个受试者脉搏波传导时间与收缩压具有良好的线性关系（r2=0.91±0.06），线性模型的检测误差为（3.48±1.69）mmHg，且具有较好的稳定性。但对于不同受试者，很难建立统一的线性模型（r2=0.14）。结论基于个性化脉搏波传导参数的连续血压测量方法是可行的，有望实现无袖带的连续血压测量。