探讨使用CT对比剂在肺循环动静脉中峰值r时间差值评价慢性心衰的可行性

摘要

Objective To study the feasibility of CT TestBolus in achieving of peak-time interval of CT contrast medium between pulmonary artery and vein as an Objective indicator for chronic heart failure. Methods We retrospectively collected 60 patients, who need to clndergo CT scan with contrast medium. They were divided into two groups (control group with normal heart and test group with chronic heart failure). CT TestBolus was applied to both groups. Then the acquired attenuation time curve was analyzed by DynEva and the peak-time interval of contrast medium between pulmonary artery and vein (ΔTp) were calculated. The relationship between left ventricular ejection fraction (LVEF) of B ultrasonic andΔTp was evaluated by using pairedt tests.Results TheΔTp and LVEF in the test group were significantly changed, and there were significant differences between the control group and the test group.Conclusion ΔTp acquired by CT TestBolus is of great value in evaluation of chronic heart failure, which can be used in assessing of severity for chronic cardiac failure.%目的 研究用CT TestBolus技术获取CT对比剂在肺动、静脉达峰时间的差值(△Tp),作为慢性心力衰竭客观量化评价参数的可行性.方法 回顾性搜集60例病人,分为正常组和实验组.所有患者行TestBolus扫描,获取的图像在DynEva软件中分析,得出CT对比剂强化值-时间曲线,测到每组△Tp值,并初步认定△Tp值≥7 s为异常.与超声左室射血分数(LVEF)进行配对t检验统计学分析,评价各组差异,△Tp值和LVEF值的关系.结果 实验组的△Tp值、LVEF值比正常组显著改变,两组△Tp值、LVEF值具有统计学意义(P<0.05).在正常组中,△Tp值与LVEF值之间的差异无统计学意义(P>0.05).结论 CT对比剂在肺循环中的峰值时间△Tp是评价慢性心力衰竭病人心血管系统循环状态的良好指标,可用于评价慢性心力衰竭病情的严重程度.