神经内镜下经蝶入路手术治疗蝶窦侵袭性垂体腺瘤

摘要

Objective:To investigate surgical strategy and skil s of Neuroendoscopic transsphenoidal surgery on Sphenoidal Invasive pituitary adenomas. Methods:Clinical data of 28 patients with Sphenoidal Invasive pituitary adenomas undergoing a Neuroendoscopic transsphenoidal surgery were analyzed retrospectively. The degree of tumor resection and postoperative symptoms were summarized and analyzed. Results: The postoperative pathological results showed that non-functional adenomas was in 11 patients, GH adenomas in 6, GH/PRL adenomas in 4, PRL adenomas in 4,FSH/LH adenomas in 2,and ACTH adenoma in 1. MRI reexamination was performed 3 months after surgery, total tumor removal was achieved in 5 patients,subtotal removal in 5, most removal in 13, and partial removal in 5. Conclusion:Neuroendoscopic transsphenoidal surgery should be the ifrst treatment choice for patients with Sphenoidal Invasive pituitary adenomas.%目的：探讨神经内镜下经蝶入路手术治疗蝶窦侵袭性垂体腺瘤手术技术及疗效。方法：回顾性分析28例罹患蝶窦侵袭性垂体腺瘤并在神经内镜辅助下行经蝶入路手术治疗的患者临床资料，对手术切除程度、术后恢复情况等进行总结。结果：术后病理结果提示：无功能腺瘤11例；单纯生长激素腺瘤6例；生长激素腺瘤合并泌乳素腺瘤4例；泌乳素腺瘤4例；FSH/LH腺瘤2例，ACTH腺瘤1例。术后3月复查 MRI肿瘤全切5例，次全切除5例，大部切除13例，部分切除5例。结论：对蝶窦侵袭性垂体腺瘤病例而言，神经内镜下经蝶入路手术治疗创伤减少，疗效确切，应作为首选治疗方法。