[Objective] To observe and evaluate the feasibility and safety of single-port laparoscopic hysterectomy in clinical surgery. [Methods] Forty-two patients with benign uterine disease were randomly divided into two groups. Research group (20 cases) underwent transumbilical single-port laparoscopic hysterectomy (TSPLH), control group (22 cases) underwent traditional 4-port laparoscopic hysterectomy (LCH). Perioperative complications and parameters were observed and analyzed. [Results] TSPLH and traditional LCH were both performed successfully in the two groups. There was no statistically difference in blood loss, conversion rate, gas pass time, activity time, postoperative analgesic rate between two groups. But regarding hospital stay, postoperative fever rate, patient satisfaction score, there was statistically significant difference between two groups (P <0.05). The operation time in the TSPLH group was longer than those in the control group (P <0.05). All subjects recovered from the operation and no postoperative complication occurred during the period of one through six month follow-up. [ Conclusions ] TSPLH is a feasible and safe method for hysterectomy, The patients should be selected strictly, procedure should be performed by experienced endoscopic surgeon.%目的 探讨经脐单孔腹腔镜全子宫切除术的安全性与可行性.方法 在严格掌握适应证的前提下,为42例良性子宫疾病患者行腹腔镜手术,其中20例行单孔腹腔镜全子宫切除术(TSPLH),22例行传统4孔腹腔镜全子宫切除术(LCH),比较两组患者围手术期情况,将两组结果进行对比分析,以充分阐释单孔腹腔镜手术的优缺点.结果 两组手术均获得成功,术中失血量、术中转开腹率、术后排气时间、术后首次下床活动时间、术后镇痛率、切孔部位的感染、术后切孔疝发生率在两组间差异无显著性；TSPLH组术后住院时间、术后发热率、疼痛模拟评分(VAS)、以及患者的满意度评分均优于传统腹腔镜手术组,两组间差异有显著性(P＜0.05)；TSPLH组的手术时间比LCH组长(P＜0.05).在1～6个月的随访期内无1例术后并发症发生.结论 经脐单孔腹腔镜全子宫切除术是一种安全可行更加微创的手术方法,在实施时应注意严格选择病例、循序渐进,且由经验丰富的腔镜医生施术.
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