目的 研究双气囊内镜(DBE)检查在小肠疾病诊治中的临床价值.方法 采用回顾性分析法纳入2006年3月-2014年4月天津医科大学总医院收诊的怀疑小肠病变的344例患者为研究对象,患者表现的临床症状有不同程度的腹痛、腹胀、恶心呕吐、腹泻和黑便等,对所有患者实施DBE检查,344例患者行DBE检查397次.结果 ①检查时的不良反应发生率仅为4.53%;检查后344例患者均未发生并发症;②除214例经DBE检查出阳性结果外,另外130例患者经DBE检查呈阴性的患者,经胶囊内镜和小肠CT扫描方法共同诊断为小肠病变的患者28例,剩余102例患者小肠检查未见明显病变,本次研究中DBE的漏诊率为8.13%,其中以息肉、血管畸形病灶为主;③344例患者中共有242例患者确诊患有小肠疾病,其中以肿瘤、溃疡和息肉疾病为主,且肿瘤和溃疡疾病的DBE检查率均大于小肠息肉疾病的DBE检查率,差异具有统计学意义(P<0.05).结论 DBE检查是小肠疾病诊治中较为安全有效的方式,值得临床推广和应用.%Objective To study the clinical value of double balloon endoscopy (DBE) in diagnosis and treatment of intestinal diseases. Methods Clinical data of 344 patients suspected of small bowel lesions from March 2006 to April 2014 was retrospectively analyzed. All the patients clinical manifestations including varying degrees of abdominal pain, bloating, nause and vomiting, diarrhea. The 344 patients underwent DBE for 397 times. Results The incidence of adverse reactions in checking was only 4.53%, and there was no complications occurred after checking. Positive results shown in 214 cases by DBE, the other 130 patients shown negative results. While 28 of the other 130 patients were found small bowel lesions by capsule endoscopy and CT scans, the remaining 102 cases had no obvious abnormalities. The misdiagnosis rate of DBE was 8.13%, and mainly focuses on polyps and vascular malformation. 242 of the 344 patients were diagnosed with intestinal diseases, and mostly of them were tumor, ulcers and polyps. The detect rate of DBE examination for tumor and ulcer diseases was greater than that of small intestinal polyposis, the difference was statistically significant (P < 0.05). Conclusion DBE in diagnosis and treatment of intestinal diseases is a relatively safe and effective way. It is worthy being popularized and applied.
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