OBJECTIVE To evaluate effects on optic atrophy (OA) of different causes by traditional Chinese medicine treatment. METHODS According to the data of etiology classification of 243 OA patients with 415 eyes, the effect of comprehensive treatment of traditional Chinese medicine (TCM) was evaluated. RESULTS After treat-ment with TCM, visions of 193 eyes were improved, and effective rate was 46.5%. Anterior ischemic optic neuropathy (AION), effective rate was 68.8%, followed by Leber’s hereditary optic neuropathy (LHON), optic nerve inflamma-tory, retinitis pigmentosa, glaucoma, retinal artery obstruction, effective rate was 61.4%, 53.0%, 40.9%, 40%, and 40% respectively. Unknown reason, drug intoxication, trauma, other, the tumor oppression were 38.7%, 37.5%, 32.3%, 25.0%, and 23.1%respectively. CONCLUSIONS TCM treatment for OA was effective, and AION, LHON, optic inflammatory OA were the most effective.%目的：评价中医治疗不同病因视神经萎缩（OA）的效果。方法将243例（415只眼）OA患者按病因分类，并对中医综合治疗的效果进行评估。结果经中医综合治疗后视力改善193只眼，整体有效率为46.5%。前部缺血性视神经病变（AION）有效率最高为68.8%，其他病因OA的有效率依次为Leber遗传性视神经病变（LHON）61.4%，视神经炎53.0%，视网膜色素变性40.9%，青光眼40.0%，视网膜动脉阻塞40.0%、不明原因性38.7%、药物中毒37.5%、外伤32.3%、其他25.0%、肿瘤压迫23.1%。结论中医方法治疗OA有效，其中AION、LHON、视神经炎性OA有效率均超过50%，疗效相对较好。
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