联合检测降钙素原，C-反应蛋白及D-二聚体在慢性阻塞性肺病中的临床应用

摘要

Objective To study the PCT original, CRP and D - dimer in COPD in the clinical application value. Methods Collected from COPD patients with acute exacerbation period (AECOPD) 84 cases of patients with COPD stabilization and this 26 cases, PCT, CRP, D - dimer and the value of the WBC level in the diagnosis of chronic obstructive pulmonary disease (COPD) are compared and analyzed. Results Compared with patients with CODP stabilization, AECOPD patients PCT, CRP, D - dimer and significantly increased the WBC level, positive rate of PCT and CRP level patients with COPD plateau elevated obviously, difference was statistically significant (P﹤ 0.05); In patients with AECOPD, PCT, the positive, the below PCT negative groups and the mortality rate is higher than negative group, difference was statistically significant (P﹤ 0.05). Conclusion PCT, CRP, D - dimer and detection of the level of WBC in the progression of COPD has important clinical value in the process.%目的：探讨降钙素原，C-反应蛋白及D-二聚体在慢性阻塞性肺病中的临床应用价值。方法收集我院COPD急性加重期患者84例及门急诊就诊的COPD稳定期患者26例，进行PCT、CRP、D-二聚体及WBC水平在诊断慢性阻塞性肺病的价值进行比较和分析。结果与CODP稳定期患者相比，AECOPD患者的PCT、CRP、D-二聚体及WBC水平明显升高，PCT及CRP水平阳性率较COPD稳定期患者明显升高，差异有统计学意义（P﹤0.05）；AECOPD患者中，PCT阳性组的好转率低于PCT阴性组，而死亡率高于阴性组，差异有统计学意义（P﹤0.05）。结论 PCT、CRP、D-二聚体及WBC水平的检测，在COPD的病情进展过程中具有重要的临床应用价值。