胼胝体前部切开和胼胝全切开治疗儿童难治性癫痫的效果对比

摘要

目的：探讨难治性癫痫患儿胼胝体切开长度的不同产生的手术效果。方法回顾性研究2013年1月～2014年4月我院收治的38例患有难治性癫痫的儿童，其中24例行胼胝体前部切开术，14例行胼胝体一期全切开术，术后均随访1年，采用改良的Engel分级评估手术效果。结果胼胝体前部切开组：EngelⅠ级5例、EngelⅡ级8例、EngelⅢ级9例、EngelⅣ级2例；胼胝体一期全切开组：EngelⅠ级6例、EngelⅡ级7例、EngelⅢ级1例、EngelⅣ级别0例。结论对于难治性癫痫患儿，胼胝体一期全部切开比胼胝体前部切开更加有效，应在术前充分评估病情及风险的基础上，合理选择手术方式。%ObjectiveTo compare the efficacy of anterior corpus calosotomy and ful corpus calosotomy for treatment in children with intractable epilepsy. Methods Retrospectively analyzed the clinical files of 38 children with intractable epilepsy from January 2013 to April 2014 performed by anterior corpus calosotomy. Patients were folowed up for 1 year,and the effect of the surgery was evaluated according to the modified Engel grading.Results Patients treated with anterior corpus calosotomy: Engel class I 5 cases,Engel class II 8 cases,Engel class III 9 cases,Engel class IV 2 cases. Patients treated with ful corpus calosotomy:Engel class I 6 cases,Engel class II 7 cases,Engel class III 1 cases,Engel class IV 0 cases.Conclusion Anterior corpus calosotomy showed better efficacy in treating children with intractable epilepsy than ful corpus calosotomy.