血清促甲状腺素水平与甲状腺结节良恶性的相关性研究

摘要

Objective To investigate the correlation between serum thyroid stimulating hormone level and benign and malignant thyroid nodules. MethodsA retrospective analysis of the clinical data of 90 cases of patients with thyroid nodules,according to the postoperative pathological results,devided into thyroid adenoma group(TA),nodular goiter(NG)group and thyroid carcinoma(TC) group. Thyroid function test was observed and to observe the correlation between the level of thyroid stimulating hormone and the incidence of benign and malignant thyroid nodules.ResultsThe average level of TSH in TC group was significantly higher than that in TA group and NG group(P< 0.05). With the increase of TSH level,the percentage of patients in the TC group increased gradually(P< 0.05). The average level of TSH in patients with lymph node metastasis had no difference than those without lymph node metastasis (P> 0.05).ConclusionPreoperative serum TSH level can be used as an important indicator to determine the benign and malignant thyroid nodules.%目的：探讨血清促甲状腺素水平与甲状腺结节良恶性的相关性。方法回顾性分析90例甲状腺结节患者的临床资料，按术后病理结果分为甲状腺腺瘤（TA）组，结节性甲状腺肿（NG）组和甲状腺癌（TC）组，进行甲状腺功能测定，观察促甲状腺素水平变化与甲状腺良恶性结节发生率的相关性。结果（1）TC组的TSH平均水平高于TA组和NG组（P<0.05）。（2）随着TSH水平的不断升高，TC组患者所占百分比呈逐渐增加趋势（P<0.05）。（3）有淋巴结转移者血清TSH平均水平与无淋巴结转移者，差异无统计学意义（P>0.05）。结论术前血清TSH水平可做为判定甲状腺良恶性结节的一个重要指标。