呼吸道病毒检测在儿童呼吸道感染中的临床意义

摘要

目的：研究呼吸道病毒检测在儿童呼吸道感染中的临床意义。方法选取我院2013年4月～2014年5月的120例呼吸道感染患儿作为研究对象，按年龄分为8月～4岁、4～7岁、7～10岁，3组。采用目前医学常用的酶联免疫吸附测定（ELISA）法对患儿血清免疫球蛋白LgM进行检测。记录患儿腺病毒（ADV）、呼吸道合胞病毒（RSV）、甲型流感病毒（IFA）、乙型流感病毒（IFB）四类抗体阳性率检出情况。结果阳性检出率8月～4岁组76.3%，4～7岁组77.5%，高于7～10岁组的33.3%，差异具有统计学意义（P<0.05）；血清LgM指标检测均有阳性，RSV阳性检出率34.2%高于ADC（21.7%）、IFA（15.0%）、IFB（19.2%），差异具有统计学意义（P<0.05）。结论呼吸道病毒检测能有效检测患儿相关血清指标，有助于病原体确定和临床治疗方法的选择。%Objective To study the clinical significance of detection of respiratory viruses in children with respiratory tract infections.MethodsFrom April 2013 to May 2014,120 patients with respiratory tract infection were selected as the research object. According the age,the children were divided into 8 months to 4 years old,4 to 7 years old and 7 to 10 years old of 3 groups. The enzyme linked immunosorbent assay (ELISA) method was frequently used in present medical science to detect serum immunoglobulin LgM in children. Adenovirus(ADV),respiratory syncytial virus(RSV),influenza A virus (IFA)and influenza B virus (IFB) of four kinds of antibodies were recorded.ResultsThe positive detection rate in the 8 months to 4 years old group was 76.3% and in the 4 to 7 years old group was 77.5%,which were significantly higher than 33.3% in the 7 to 10 years old group and the difference was statisticaly significant(P< 0.05). The detection of serum LgM indexes was positive. The positive detection rate of RSV was 34.2%,which was higher than ADC(34.2%),IFA(15.0%)and IFB(19.2%),and the differences were statisticaly significant(P< 0.05).ConclusionThe respiratory virus detection can effectively detect the related serum indexes in children,which is helpful for the detemination of pathogen and selection of clinical treatment method.