目的：探讨利用胱抑素C（CysC）和尿微量清蛋白（mALB）水平测定在糖尿病早期诊断方面的作用。方法对我院近期收治的100例糖尿病肾病患者的临床资料和治疗过程进行回顾性分析，根据患者的病情特点和肾功能情况，将患者分为A组和B组，每组50例，其中A组为肾功能正常糖尿病患者。再选50例健康者作为对照组，对这些患者进行胱抑素C和尿微量清蛋白水平的测定并进行比较分析。结果经检测，B组患者血清胱抑素和尿微量清蛋白水平较高，与A组和对照组相比，差异有统计学意义（P<0.05）；同时，A组患者的测量结果也高于正常者。结论胱抑素C和尿微量清蛋白在进行糖尿病肾病的早期诊断方面敏感性较高，可做到早期发现，早期治疗，给患者带来好处。%Objective To explore the use of cystatin C(CysC)and urinary albumin(mALB)levels in the early diagnosis of diabetes mel itus. Methods The clinical data and therapeutic process of 100 patients with diabetic nephropathy were retrospectively analyzed. The patients were divided into A group and B group according to characteristics of the disease and the renal function, 50 patients in each group. The patients of A group was diabetic patients with normal renal function. 50 cases of healthy people as A group. Cystatin C and urinary microalbumin levels were measured and compared. Results The level of Cystatin C and urinary microalbumin of B group were higher than that of A group and control group, the differences were significant(P<0.05). The level of Cystatin C and urinary microalbumin of A group was significantly higher than that of control group. Conclusion The detection means of cystatin C and urinary microalbumin in diabetic nephropathy is higher sensitivity. The detection means can help the patients to achieve early detection and early treatment.
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