心脏起搏后B型利钠肽的变化及其临床意义

摘要

Objective To investigate the changes and clinical significance of B-type natriuretic peptide in cardiac pacing.Methods Former permanent cardiac pacing for 86 cases of patients with postoperative 1 d,7 d and after surgery a month,three months,B-type natriuretic peptide levels in six months, respectively,were measured and compared at different times,in different under the pacing mode,change B-type natriuretic peptide levels.Results Cardiac function class III,IV grade patients with any kind of pacing mode,at different times B-type natriuretic peptide levels were significant changes, significant differences between the two groups(P<0.05),there are statisticaly significant.Conclusion In need of patients undergoing cardiac pacing therapy,if patients with concomitant heart failure,you need to select the physiologic pacing; atrioventricular conduction in patients with normal function if you can select AAI(R)pacing mode.%目的：探讨心脏起搏后B型利钠肽的变化及其临床意义。方法对86例心脏永久起搏患者术前、术后1 d、术后7 d以及术后1个月、3个月、6个月的B型利钠肽水平分别进行测定，并比较不同时期，在不同起搏方式下，B型利钠肽水平的变化。结果心功能III级、IV级患者采用任何一种起搏方式，在不同时期B型利钠肽水平均有较大变化，组间比较差异明显（P<0.05），有统计学意义。结论在对需要行心脏永久起搏患者的治疗中，若患者同时合并心功能不全，则需选择生理性起搏方式；若患者房室传导功能正常，则可选择AAI（R）起搏方式。