无创通气治疗慢性阻塞性肺疾病合并II型呼吸衰竭的临床研究

摘要

Objective To research and evaluate the clinic effect of BiPAP on chronic obstructive pulmonary disease(COPD) combined with II respiratory failure.Methods 84 cases patients with COPD combined with II respiratory failure from July 2010 to July 2014 in our hospital were randomly divided into control group and treatment group ,each group has 42cases The control group applied basic treatment method and the treatment group applied BiPAP at the same time.To compared the effect rate of treatment and blood gas analysis index of pH、PaO2 and PaCO2 between two groups.Results The effect rate of treatment of control group was 57.1%,the effect rate of treatment of treatment group was 88.1 %,the difference was significant (P<0.05); The index of pH、PaO2 and PaCO2 of treatment group was better than that of control group fter treatment,the difference was significant (P<0.01).Conclusion Application of BiPAP on the treatment of COPD combined with II respiratory failure could effectively reduce the patient's clinical symptoms ,could improve rapidly the patient's blood gas analysis index ,could improve the patient's quality of life. It was the ideal methods of noninvasive,safe and reliable.which have the widely prospect of clinical application.%目的：研究评价双水平无创正压通气（BiPAP）治疗慢性阻塞性肺疾病合并II型呼吸衰竭患者的临床效果。方法随机将2010年7月～2014年7月我院收治的慢性阻塞性肺疾病合并II型呼吸衰竭患者84例分成对照组和治疗组各42例，对照组采用基础治疗方法，治疗组同时采用BiPAP治疗方法，对两组治疗显效率和pH值、PaO2和PaCO2血气分析指标进行比较。结果对照组的治疗显效率为57.1%、治疗组的治疗显效率为88.1%、两组比较差异有统计学意义（P<0.05）；治疗后治疗组pH值、PaO2和PaCO2血气分析指标均显著的优于对照组，两组比较差异有显著统计学意义（P<0.01）。结论 COPD合并II型呼吸衰竭患者应用BiPAP治疗，能够使患者的临床症状得到有效地缓解，能够使患者的血气分析指标快速的得到改善，能够使患者的生活质量得到提高，是理想的无创、安全、可靠的治疗手段，具有广泛的临床应用前景。