氯吡格雷治疗急性缺血性脑卒中的疗效及对血浆大内皮素-1和血清脂蛋白-α的影响

摘要

Objective To discuss the clinical effect of clopidogrel in treating acute ischemic stroke. Methods Selected 200 hospitalized acute ischemic stroke patients, divide them into the observation group and the control group, patients in each group were 100 cases,the control group was given routine treatment ,the observation group received clopidogrel tablets on the basis of the control group.ResultsThe NIHSS scores, ADL scores and VMCA of the observation group 3 months and 6 months after treatment were significantly better than that of the control group, and the plasma big ET-1、Lp-α level of the observation group after treatment were significantly lower than that of the control group, and both of the differences were statisticaly significant(P<0.05).ConclusionClopidogrel is effective in treating acute ischemic stroke clinicaly.%目的：探讨氯吡格雷治疗急性缺血性脑卒中的临床效果。方法选取我院收治的急性缺血性脑卒中的患者200例，随机分为观察组100例和对照组100例，两组患者均给予常规治疗，观察组患者在此基础上给予氯吡格雷片治疗。结果观察组治疗后3个月及6个月时的NIHSS评分、ADL评分及VMCA优于对照组，观察组经过治疗后血浆大内皮素-1、血清脂蛋白-α水平低于对照组，差异均具有统计学意义（P＜0.05）。结论氯吡格雷治疗急性缺血性脑卒中临床效果显著。