高压氧治疗新生儿缺血缺氧性脑病临床观察

摘要

Objective The paper explores the therapeutic effects of hyperbaric oxygenation therapy on hypoxic ischemic encephalopathy(HIE)of neonates.Methods The research chose 100 cases of HIE neonates from the hospital and divided them randomly into the observation group and the control group of which each group had 50 cases. The control group received the routine treatment while the observation group received the additional hyperbaric oxygenation therapy on this basis. The research observed the therapeutic effects of two groups. Results According to the information obtained in follow-up visits after the treatment, the observation group’s mental development index(MDI)and physical development index(PDI)in the 6 month and the 12 month after the treatment were significantly higher than those of the control group(P<0.05),moreover,the difference of two groups in NBMA score and MMP-9 value both had statistical significance(P<0.05).Conclusion The hyperbaric oxygenation therapy has good clinical effects on HIE and has the application value.%目的：探讨高压氧治疗新生儿缺血缺氧性脑病的效果。方法选择我院100例新生儿缺血缺氧性脑病患儿，随机分为观察组和对照组，每组患者均为50例，对照组给予常规治疗，观察组在此基础上给予高压氧治疗，观察两组患儿治疗效果。结果治疗结束后随访，观察组患者在治疗结束后第6、12个月的智力发育指数（MDI）和运动发育指数（PDI）高于对照组（P＜0.05），治疗后两组患儿NBNA评分、MMP-9值差异均有统计学意义（P＜0.05）。结论高压氧治疗新生儿缺血缺氧性脑病，效果更好。