脑梗死患者血清同型半胱氨酸和高敏C-反应蛋白水平变化及临床意义

摘要

Objective To evaluate patients with acute cerebral infarction serum homocysteine levels and clinical significance and high sensitivity C-reactive protein.Methods 88 cases of cerebral infarction patients from July 2011 to July 2013 as the observation group were treated the same period selected outpatients were 76 cases of healthy control group, using automatic biochemical ana-lyzer and serum homocysteine high sensitivity C-reactive protein levels.Results The serum homocysteine in patients in the obser-vation group, high-sensitivity C-reactive protein levels were significantly higher, the difference was statistically significant (P<0.05). Observed serum homocysteine, high sensitivity C-reactive protein levels with the severity of neurological deficits and in-creased the difference between groups was statistically significant (P<0.05).Conclusion Serum homocysteine and high-sensitivity C-reactive protein closely related to elevated levels of cerebral infarction, both collaborative detection will help in the early diag-nosis and evaluation of efficacy.%目的：探讨急性脑梗死患者血清同型半胱氨酸及高敏C-反应蛋白的水平变化及临床意义。方法选取2011年7月-2013年7月收治的88例脑梗死患者作为观察组，同期选取本院门诊健康体检者76例为对照组，采用全自动生化仪检测血清同型半胱氨酸及高敏C-反应蛋白水平。结果观察组患者血清同型半胱氨酸、高敏C-反应蛋白水平明显高于对照组，差异有统计学意义(P<0.05)。观察组血清同型半胱氨酸、高敏C-反应蛋白水平随着神经功能缺损程度的加重而升高，组间比较差异有统计学意义(P<0.05)。结论血清同型半胱氨酸和高敏C-反应蛋白水平升高与脑梗死发病密切相关，两者协同检测将有助于早期诊断和评价疗效。