舒芬太尼联合丙泊酚静脉麻醉在无痛结肠镜检查中的效果观察

摘要

Objective To investigate the safety and anesthesia effects of intravenous anesthesia with sufentanil combined with propofol during painless colonoscopy. Methods 80 eligible patients were selected and randomly divided into observation group and control group, 40 patients each group; the observation group used intravenous anesthesia with sufentanil combined with propofol, while the control group used intravenous anesthesia with fentanyl combined with propofol, and the vital sign changes and anesthe-sia effects were compared.Results Before and after colonoscopy, the HR, RR, MAP and SpO2 in the patients of the observation group were stable, and the differences were statistically insignificant (P>0.05). The HR, MAP and SpO2 in the patients of the con-trol group during colonoscopy were decreased when compared with those of the same group before anesthesia and those of the ob-servation group during colonoscopy, and the differences were statistically significant (P<0.05). The palinesthesia time and recovery time in the patients of the observation group were both shorter than those of the control group, and the differences were statistically significant (P<0.05);the anesthesia induction time and colonoscope access time in the patients of the observation group were simi-lar with those of the control group, and the differences were statistically insignificant (P>0.05). The dose of used propofol of the observation group was less than that of the control group, anesthesia effects of the observation group were significantly better than that of the control group, and the difference was statistically insignificant (P>0.05). Conclusion Intravenous anesthesia with sufen-tanil combined with propofol during colonoscopy has positive analgesic effects and stable hemodynamic parameters, and can re-duce the dose of propofol.%目的：探讨舒芬太尼联合丙泊酚静脉麻醉在无痛结肠镜检查中的麻醉效果及安全性。方法选择符合标准的患者80例，随机分为观察组和对照组各40例，观察组采用舒芬太尼联合丙泊酚静脉麻醉，对照组采用芬太尼联合丙泊酚静脉麻醉，比较麻醉效果及生命体征变化。结果观察组患者检查前后HR、RR、MAP及SPO2平稳，差异无统计学意义（P＞0.05）。对照组检查中HR、MAP、SPO2与麻醉前、观察组检查中比较，均不同程度下降，差异有统计学意义（P＜0.05）。观察组苏醒时间（0.76±0.23）min、恢复时间（16.15±2.32）min，均短于对照组的（1.20±0.35）min、（20.93±3.86）min，差异有统计学意义（P＜0.05）；二者麻醉诱导时间和进镜时间相似，差异无统计学意义（P＞0.05）。观察组患者丙泊酚应用总量（1.62±0.53）g，对照组患者丙泊酚应用总量（2.14±0.69）g，差异有统计学意义（P＜0.05）。观察组患者麻醉效果优37例、良3例，对照组麻醉效果优29例、良10例和差1例，差异有统计学意义（P＜0.05）。结论结肠镜检查应用舒芬太尼联合丙泊酚静脉麻醉，镇痛效果确切，血流动力学稳定，减少丙泊酚的用药剂量，值得临床推广应用。