目的：对伊宁市2013年135例阴性静脉吸毒人群队列展开研究活动，分析吸毒人群危险因素。方法选取2013年内医院检测HIV阴性的吸毒人群队列135人，对队列内所有人每3个月随访调查高危吸毒行为以及性行为情况，并采集血样进行艾滋病、丙肝、梅毒抗体检测。结果随访调查1年，135例静脉吸毒人群中有23人失访、11人提前中止调查，仅有101人坚持随访，队列保持率为74.8%。艾滋病抗体阳性2例，HIV阳性率为2.0%，通过条件分析发现，安全套的使用、性伴侣吸毒与HIV抗体转阳有统计学意义(P<0.05)；丙肝抗体阳性47例，HCV阳性率为46.5%，通过条件分析发现，吸毒与HCV抗体转阳有统计学意义(P<0.05)；梅毒抗体阳性2例，RPR阳性率为2.0%，通过条件分析发现，性别与RPR抗体转阳有统计学意义(P<0.05)。结论通过伊宁市静脉吸毒人群队列调查发现，吸毒人群中的丙肝发生率较高，需要针对其危险因素进行对照干预，以遏制传染性病毒的传播速度。%Objective To carry out the research of 135 negative intravenous drug users queue in Yining in 2013 and ana-lyze the risk factors of drug users. Methods 135 drug users detected with negative HIV in our hospital in 2013 were select-ed, and the high-risk drug taking behavior and sex behavior of them were surveyed by follow-up every three months, and the blood samples were collected for AIDS, Hepatitis C and Anti-TP detection. Results One-year follow-up survey showed that in the 135 cases of intravenous drug users, 23 cases lost to follow-up, 11 cases proposed to suspend investigation, only 101 cases insisted on research survey, and the queue retention rate was 74.8%, AIDS antibody of 2 cases was positive and the HIV positive rate was 2.0%, the condition analysis showed that the use of condoms, drug taking of sex mate and HIV antibody becoming positive had statistical significance, P<0.05, anti-HCV of 47 cases was positive, and the HCV positive rate was 46.5%, and the condition analysis showed that drug taking and HIV antibody becoming positive had statistical sig-nificance, P<0.05, and the anti-TP of 2 cases was positive, and the RPR positive rate was 2.0%, and the condition analysis showed that the gender and PRP antibody becoming positive had statistical significance, P<0.05. Conclusion The survey of intravenous drug users queue in Yining shows that the incidence rate of Hepatitis C in the drug users is high, and we need to carry out corresponding intervention for risk factors in order to prevent the spread speed of infectious viruses.
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