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艾滋病合并结核病患者与T淋巴细胞之间的关系探究

     

摘要

Objective To analyze the relationship between AIDS patients with tuberculosis and T lymphocytes. Methods 50 patients with AIDS and tuberculosis were randomly selected from our study. All of them were tested for CD4+ levels. According to the results of CD4+ measurement, 30 patients <100/mm3 were considered as observation group and ≥100/mm3 of 20 patients as the control group, and the clinical data of the two groups were compared and analyzed. Results The incidence of tuberculous pleurisy, nodal brain, lymphatic tuberculosis, and hematogenous disseminated tuberculosis in the observation group were 20.00%, 33.33%, 3.33%, and 23.33%, respectively, which were 30.00%, 15.00%, 20.00%, and 0.00% with the control group. It was statistically significant (χ2=4.877 7, 5.596 0, 6.208 3, 7.710 1, P=0.012 6, 0.041 0, 0.000 2,<0.000 0); the sputum smear was positive for acid-fast staining, positive for the test, and the positive rate of PPD was 13.33%. 13.33%, 10.00%, were lower than the control group 25.00%, 30.00%, 25.00% (χ2=4.366 0, 8.841 1, 4.466 5, P=0.013 9, 0.020 4, 0.036 4). Conclusion The lower the CD4+ level, the greater the risk of tuberculosis, and the greater likelihood of cerebral palsy and hematogenous disseminated tuberculosis.%目的 分析艾滋病合并结核病患者与T淋巴细胞之间的关系.方法 方便选取该市50例艾滋病合并结核病患者为该研究对象,均进行CD4+水平测定,根据CD4+测定结果分组,<100/mm3的患者共30例,视作观察组,≥100/mm3的患者共20例,视作对照组,对两组临床各项资料进行比较分析.结果 观察组结核性胸膜炎、结脑、淋巴结核、血行播散型肺结核出现率分别为20.00%、33.33%、3.33%、23.33%,均与对照组30.00%、15.00%、20.00%、0.00%差异有统计学意义(χ2=4.877 7、5.596 0、6.208 3、7.710 1,P=0.012 6、0.041 0、0.000 2、<0.000 0);观察组痰涂片抗酸染色阳性、结明试验阳性、PPD阳性率分别为13.33%、13.33%、10.00%, 均低于对照组25.00%、30.00%、25.00%(χ2=4.366 0、8.841 1、4.466 5,P=0.013 9、0.020 4、0.036 4).结论CD4+水平越低,结核病出现的风险越大,且出现结脑、血行播散型结核病艾滋病的可能性更大.

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