目的 评价驱铅药物与综合干预对儿童铅中毒的干预效果. 方法 整群选择该院2010年1月—2013年6月血铅水平在100μg/L以上的患儿300例,随机分为对照组和观察组,每组150例.干预前进行血铅检测留样,对两组患儿均进行驱铅药物治疗,对观察组患儿实施健康教育、饮食干预和行为干预等综合干预措施,干预4个月后复检血铅. 结果 观察组患儿铅中毒相关防护知识调查得分、饮食及卫生行为习惯得分均高于对照组患儿,比较差异有统计学意义(P<0.05). 经治疗后,观察组出院后6个月的血铅水平明显低于对照组,比较差异有统计学意义(P<0.05). 结论 在常规驱铅药物治疗基础上加强饮食干预可有效纠正患儿的不良饮食习惯和不良卫生习惯,降低血铅水平,具有临床推广应用价值.%Objective To evaluate the effect of removing lead drugs and comprehensive intervention on children with lead poison-ing. Methods 300 cases with the blood lead level over 100 μg/L admitted in our hospital from January 2010 to June 2013 were selected and randomly divided into the control group and the observation group with 150 cases in each. Before intervention, both groups were given the blood lead level test and treated by the removing lead drugs. The children in the observation group were given health education, dietary intervention, behavioral intervention and so on additionally. The blood lead level was tested in the two groups again 4 months after intervention. Results The scores of the knowledge related to lead poisoning, dietary and hygienic and behavioral habit of the observation group were higher than those of the control group, respectively with statistically significant difference (P<0.05). After treatment, the blood lead level 6 months after discharge of the observation group was much lower than that of the control group with statistically significant difference (P<0.05). Conclusion Dietary intervention combined with the con-ventional removing lead drugs treatment can effectively correct the bad dietary and hygienic habits and reduce the blood lead level with the value of clinical application and promotion.
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