初发及复发性前循环缺血性脑卒中患者颈动脉粥样硬化斑块对比研究

摘要

Objective To compare the difference of atherosclerotic plaque between initial and recurrent cerebral infarction in carotid artery system. Methods 98 cases of first cerebral infarction in carotid artery system and 132 cases of recurrent cerebral in-farction in carotid artery system were included in the study. The number and distribution of the atherosclerotic plaque were col-lected with color Doppler imaging. The character of atherosclerotic plaque was analyzed. Results The incidence of carotid plaque and the rate of artery stenosis of blood vessels in the recurrent group were higher than those in the first cerebral infarction group(95.5%and 50.1%vs 86.7%and 21.4%,P=0.000),and most of atherosclerotic plaques in recurrent cerebral infarction group were vulnerable plaques(77.3%).Conclusion Recurrent cerebral infarction in carotid artery system is related to unstable plaque and the degree of stenosis which may be one cause of recurrent cerebral infarction in carotid artery system.%目的：研究初发及复发性前循环缺血性脑卒中患者颈动脉粥样硬化斑块的差异性。方法筛选符合条件的98例前循环初发性脑梗死(初发组)、132例前循环复发性脑梗死(复发组)进入该研究，采用彩色多普勒血流成像技术观察入组患者颈动脉粥样硬化斑块的数目及部位，记录斑块性质。结果复发性前循环脑梗死组患者斑块发生率及血管狭窄发生率明显高于初发性前循环脑梗死组（95.5%和50.1%比86.7%和21.4%，P=0.000），复发性脑梗死组斑块性质以为不稳定性斑块为主（77.3%）。结论前循环复发性脑梗死与颈动脉不稳定性粥样斑块及血管狭窄相关，不稳定斑块及颈动脉狭窄可能是引起前循环复发性脑梗死的危险因素之一。