Thirty lactating Holstein cows were used to evaluate the effect of Lactic acid bacterium on milk production, blood immunity and antioxidative activity. These cows were randomly divided into three groups: control group (basal diet); lactic acid bacterium group1 (basal diet + 15g/d/head lactic acid bacterium); lactic acid bacterium group2 (basal diet + 30g/d/head lactic acid bacterium). The experiment lasted for 56 days. The results indicated that, adding lactic acid bacterium increased the daily milk production(P<0.05), and reduced the milk somatic cell counts (P<0.05). Compared with the control group, cows in lactic acid bacterium group2 had higher (P<0.05)IgG and sCD4 contents, higher SOD and GSH-Px activities, and lower (P<0.05) MDA content in the serum. In conclusion, adding lactic acid bacterium could improve the lactation performance and enhance the immune function and antioxidant enzyme activities of dairy cows.%为研究乳酸菌对奶牛泌乳量、乳成分、免疫和抗氧化功能的影响,选择30头泌乳中期的健康荷斯坦牛,根据胎次、体重、泌乳天数及产奶量等相近的原则分为对照组、乳酸菌1组和乳酸菌2组,每组10头.对照组饲喂基础日粮,乳酸菌1组和乳酸菌2组除饲喂基础日粮外,分别饲喂乳酸菌制剂15g/(头·d)和30g/(头·d),整个试验期为56d.结果表明,添加乳酸菌能够显著提高奶牛的产奶量(P<0.05),降低乳中体细胞数(P<0.05),但对乳蛋白率、乳脂率和乳糖率均无显著影响.与对照组相比,乳酸菌2组奶牛血清中免疫球蛋白G(IgG)和可溶性CD4(sCD4)的含量,以及超氧化物歧化酶和谷胱甘肽过氧化物酶的活性均显著升高(P<0.05),而丙二醛的含量显著降低(P<0.05).综上所述,每头牛每天饲喂30g乳酸菌制剂可以提高奶牛的泌乳性能,对机体的免疫和抗氧化功能具有一定的促进作用.
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