原发性骨淋巴瘤16例临床分析

摘要

目的：为加强对原发性骨恶性淋巴瘤（PLB）的临床诊断和治疗的认识，以期得到早期诊断及积极治疗以改善预后。方法分析了16例经病理证实的PBL患者的临床资料。结果16例PBL患者中B细胞来源13例；T 细胞来源1例；ALK阴性间变性大细胞淋巴瘤1例；套细胞淋巴瘤1例。行单纯放疗者1例，单纯化疗者6例，放化疗结合者9例。16例患者中：CR8例、PR3例、SD3例、PD1例、PD后死亡1例。结论PBL主要为B细胞来源非霍奇金淋巴瘤，临床治疗以全身化疗加局部放疗的综合治疗为最佳治疗方法。%Objective In order to strengthen the primary malignant lymphoma of bone (PLB) the understanding of the clinical diagnosis and treatment, in order to get early diagnosis and active treatment to improve prognosis. Methods 16 cases confirmed by pathology were analyzed the clinical data of patients with PBL. Results 16 cases of PBL in patients with B cell source of 13 cases;T cell source in 1 case;ALK negative anaplastic large cell lymphoma in 1 case;Set of cell lymphoma in 1 case. Lines of simple radiotherapy in 1 case, pure chemotherapy 6 cases, 9 cases of radiation and chemotherapy combined with. 16 patients: CR 8 cases, 3 cases of PR, SD, 3 cases, 1 cases of PD, 1 case died after PD. Conclusion PBL is mainly for the source of B cell non-hodgkin's lymphoma, clinical treatment with systemic chemotherapy and local radiotherapy comprehensive treatment is the best treatment.