成年人膜性肾病的流行病学与病理特征研究

摘要

目的：探讨成年人膜性肾病的流行病学特点与临床病理特征。方法选取194例成年膜性肾病患者进行回顾性分析，根据其疾病类型将其分为特异性膜性肾病组107例与不典型膜性肾病组87例，统计两组患者的人口学资料与实验室检查结果，并分析其临床病理特征。结果两组患者的平均年龄与镜下血尿发生率比较，差异具有统计学意义（P＜0.05），同时，两组患者的电镜与光镜病理检查结果比较，差异具有统计学意义（P＜0.05）。结论成年人膜性肾病高发于男性人群中，单纯采用实验室检验无法准确鉴别特异性膜性肾病与不典型膜性肾病，通过临床病理检查能够有助于临床诊断与治疗。%Objective To investigate the epidemiological characteristics and clinical pathological features of membranous nephropathy in adults. Methods A total of 194 cases of adult patients with membranous nephropathy were retrospectively analyzed, according to the type of disease will be divided into speciifc membranousnephropathy group and 107 cases of atypical membranous nephropathy group 87 cases, statistics of two groups of patients' demographic and laboratory examination results, and analyze its clinical pathological features.ResultsThe average age of the two groups of patients with microscopic hematuria were compared, the difference was statistically signiifcant (P<0.05), at the same time, compared two groups of patients with electron microscopy and light microscopy pathological examination results, the difference was statistically signiifcant (P<0.05).Conclusion Adult membranous nephropathy incidence in the male population, only by laboratory tests can not accurately identify the specificity of membranous nephropathy with atypical membranous nephropathy, through clinical pathological examination can contribute to the clinical diagnosis and treatment.