18F-FDG PET/CT与螺旋CT在孤立肺结节定性诊断价值比较

摘要

目的比较18F-FDG PET/CT与螺旋CT在孤立肺结节定性诊断效果差异，探讨临床应用价值。方法选取50例肺孤立性结节患者作为研究对象，分别进行常规多层螺旋CT扫描及18F-FDG PET/CT检查。结果50例肺孤立性结节患者中经临床抗炎治疗病灶变小或消失而证实的有5例，经术后或穿刺病理证实的有45例；有24例患者被病理确诊恶性结节，恶性结节占48.00%（24/50），18F-FDG PET/CT检查诊断肺孤立性结节中恶性结节的灵敏度91.67%、特异度88.46%、准确度90.00%均显著高于常规CT检查的66.67%、65.38%、66.00%（P＜0.05）。结论18F-FDG PET/CT在肺孤立性结节良恶性的诊断价值高，可为临床制定个体化治疗方案及预后准确判断提供重要参考依据。%Objective To compare the difference of18F-FDG PET/CT and spiral CT in the qualitative diagnosis of solitary pulmonary nodules and to explore the clinical application value.Methods 50 cases of solitary pulmonary nodules were selected as the research objects, and the routine multi-slice spiral CT scanning and18F-FDG PET/CT examination were performed.Results 50 cases of solitary pulmonary nodules in patients with clinical anti-inflammatory treatment lesions or disappeared and 5 cases were conifrmed, conifrmed by surgery or biopsy in 45 cases; 24 patients were pathologically diagnosed malignant nodules, malignant nodules accounted for 48.00% (24/50), the sensitivity was 91.67%, speciifcity 88.46%, accuracy 90.00%18F-FDG PET/CT of malignant nodules diagnosis of solitary pulmonary nodules were significantly higher than that of conventional CT examination in 66.67%, 65.38%, 66.00% (P<0.05).Conclusion18F-FDG PET/CT in the diagnosis of benign and malignant solitary pulmonary nodules is high, which can provide an important reference for clinical development of individualized treatment plan and prognosis.