肾小球疾病的临床与病理分析

摘要

目的：对肾小球疾病的病理特点进行分析。方法根据2010年1月～2013年6月我院的116例肾小球成年患者进行研究分析，为患者提供肾活检，均确诊，对肾病的病理进行分析，观察病理和临床表现之间的关联性。结果全部患者中有84例原发性肾小球疾病，所占比例为72.4%；有继发性肾小球疾病32例，比例为27.6%。IgA是原发性肾小球肾炎的主要病理类型，比例为39.8%。无肾小管间质损伤和存在肾小管间质损害患者的尿白蛋白，血肌酐、血尿酸水平差异存在统计学意义（P＜0.05）。结论肾小球肾炎是肾小球常见疾病类型，不同肾小球疾病的临床表现不同，患者的尿白蛋白、血肌酐、血尿酸对肾小管间质损害起到了一定的作用。%Objective To analyze the pathological characteristics of glomerular diseases.Methods116 adult patients with glomerular from January 2010 to June 2013 in our hospital were chosen to study and analysis, provide renal biopsy for patients were diagnosed, of nephropathy pathological analysis, the correlation between clinical manifestations and pathological observation.Results In all patients, there were 84 cases of primary glomerular diseases, the proportion was 72.4%. There were 32 cases of secondary glomerular diseases, the proportion was 27.6%. IgA is the main pathological type of primary glomerulonephritis, the proportion is 39.8%. There was a statistical difference in the level of serum creatinine and uric acid in patients with no renal tubular interstitial injury and the presence of tubular interstitial lesion (P<0.05).Conclusion Glomerular nephritis is a common type of glomerular diseases, the clinical manifestations of different glomerular diseases, urinary albumin, serum creatinine, blood uric acid on renal tubular interstitial damage has played a certain role.