300例不同类型心力衰竭患者血浆BNP浓度与超敏C-反应蛋白、肌钙蛋白及冠状动脉狭窄支数的相关性研究

摘要

Objective Comparison and explore different types of heart failure (HF) plasma concentration of BNP in patients and association of high-sensitivity C-reactive protein (hs CRP), cardiac troponin I (cTnI) and coronary artery stenosis.Methods Plasma levels of BNP, hs-CRP, and cTnI were measured in 157 patients with diastolic heart failure (DHF) and 143 patients with systolic heart failure (SHF),evaluation of coronary vessels, comparative analysis of the correlation between several.Results BNP and hs-CRP levels were lower in DHF patients than in SHF patients, the level of cTnI was higher than that of SHF patients, the difference was statistically signiifcant between the two groups (P<0.05). Coronary artery stenosis in patients with heart failure number, the levels of BNP were higher (P<0.05). Conclusion Different types of patients with heart failure and plasma concentration of BNP and hs-CRP, cTnI and coronary vessels has positively correlated.%目的：比较并探究不同类型心力衰竭（HF）患者血浆BNP浓度和超敏C-反应蛋白（hs-CRP）、肌钙蛋白（cTnI）以及冠状动脉狭窄支数的相关性。方法测定157例舒张性心衰（DHF）患者和143例收缩性心衰（SHF）患者的血浆BNP、hs-CRP、cTnI浓度，评价冠状动脉狭窄支数，比较分析几者之间的相关性。结果 DHF患者的BNP和hs-CRP水平均低于SHF患者，cTnI水平高于SHF患者，对两组数据进行比较，差异有统计学意义（P＜0.05）。心衰患者冠状动脉狭窄支数越多，其血浆BNP浓度也越高（P＜0.05）。结论不同类型心衰患者血浆BNP浓度与hs-CRP、cTnI及冠状动脉狭窄支数均成正相关。