颅内原发性恶性黑色素瘤的诊治分析

摘要

目的：探讨分析颅内原发性恶性黑色素瘤的诊治效果。方法回顾性分析我院2004年1月～2014年12月我院收治的13例颅内原发性恶性黑色素瘤患者的病历资料，对其诊断方法、治疗方法以及诊疗结果进行统计分析。结果13例患者中MRI检查均显示均匀强化，肿瘤直径（1.27±0.31）cm，10例边界清晰，11例血流信号丰富，5例T1WI长信号和8例T2WI短信号；3例行次切手术，10例行全切手术，术后给予放化疗辅助治疗，随访结束时3例病情稳定，6例死亡，4例病情恶化。结论 MRI可以对颅内原发性恶性黑色素瘤进行准确诊断，外科全肿瘤切除术和放化疗辅助治疗可以有效控制病情，但预后仍较差。%Objective To explore and analysis the effects of diagnosis and treatment of primary intracranial malignant melanoma.Methods Restrospective analyzed the medical record datas of 13 cases of patients with primary intracranial malignant melanoma treated from January 2004 to December 2014 in our hospital,and the diagnostic methods, treatment methods and the results of diagnosis and treatment were analyzed statistically. ResultsMRI examination in 13 patients showed homogeneous enhancement,with tumor diameter (1.27±0.31) cm,10 cases with clear border,11 cases with abundant blood lfow signal,5 cases of T1WI long signal and 8 cases of T2WI short signal.There were 3 cases treated with routine operation,with 10 cases of total resection,who were given postoperative radiotherapy and chemotherapy, 3 cases of stable disease at the end of follow-up, 6 cases of death, 4 cases of disease progression. Conclusion MRI can accurately diagnose primary intracranial primary malignant melanoma, and surgical resection and adjuvant chemotherapy can effectively control the disease, but the prognosis is still poor.