马胚胎附植及其分子调控研究进展

摘要

Implantation is a procedure that establishes links of tissues and physiology gradually between activated blastocyst trophoblast and receivable endometrial epithelial cells. In equids, the procedure involves two distinct types of trophoblast: a minor invasive trophoblast girdle (endometrial cups) and a major non-invasive allantochorion (microcotyledonary epitheliochorial placenta). Therefore, equine is a kind of mammals that provide the opportunity to do research about both invasive and non-invasive trophoblast tissue together. A lot of molecules are involved in the procedure of implantation. Advance of researches on the characters, procedure and molecular mechanism of implantation in the mare has been reviewed, and it's useful to reduce the incidence of early pregnancy loss and abortion of mares.%胚胎附植是处于活化状态的囊胚滋养层细胞与处于接受态的母体子宫上皮细胞之间逐步建立组织和生理上联系的过程.马(马属动物)在该过程中先后存在侵入性的绒毛膜带(子宫内膜杯)和非侵入性的尿囊绒毛膜(微子叶型上皮绒毛膜胎盘),是一种集侵入性与非侵入性胚胎滋养层于一体的哺乳动物.多种分子共同调节妊娠母马的胚胎附植过程.作者综述了马胚胎附植特点、过程与相关分子调控的研究进展,对减少母马妊娠早期胚胎丢失与流产具有重要参考价值.