氨基酸卟啉锌配合物对氨基酸酯的分子识别研究

摘要

用紫外可见吸收光谱滴定方法研究了一种新型的苏氨酸卟啉锌配合物(主体)对氨基酸酯(客体)的分子识别.这种锌卟啉可以与氨基酸酯形成1：1和1：2的两种加合物.氨基酸酯的氨基首先与氨基酸残基的羧基作用形成1：1的加合物，然后与锌卟啉的中央锌原子配位形成1：2的加合物，客体分子与主体分子上的氨基酸残基之间的排斥作用以及主客体之间的色散力作用是主体分子能识别客体分子的另外两种作用。%The molecular recognition of a new kind of threonine modified porphyrinatozinc (II)(host) to amino acid esters (guest) has been detected with UV-Vis absorption spectrum titration method.This porphyrinatozinc (II) forms 1:1 and 1:2 adducts with amino acid esters.At first,the amino group of amino acid esters interacts with the carboxyl group of the amino acid residue of this porphyrinatozinc (II) to form 1:1 adducts.Then,the amino group of amino acid esters coordinates with the central zinc atom of this porphyrinatozinc (II) to form 1:2 adducts.The repulsion force between the guest and the amino acid residue of the host and London's dispersion forces between the host and the guest are the other two kinds of interactions which make this porphyrinatozinc (II) recognize amino acid esters.